| 簡 介： |
Microfluidic chip has bright application prospect in the field of chemical
and biological analysis. PMMA is the best material for microfluidic chip fabrication
because of its low cost, prominent electrochemical properties and biological
compatibility. In this work, a triple-channel microfluidic chip was designed; a nickel
mold insert with microstructure was fabricated by UV-LIGA technology, and then the
injection mold was designed and fabricated. The change in cross-section dimensions
of microchannel was chosen as evaluating indicator, and micro-injection molding
experiments were carried out. Then the influence of process parameters on crosssection
dimensions of microchannel was observed with microscope. Experiment
results demonstrated that substrate and cover plate could be manufactured in a single
injection molding process by "1+1" type mold, and the manufacturing cycle was
reduced to less than 20s, so production efficiency was greatly enhanced. Best
combination of process parameters was obtained when mold temperature was 80℃,
melt temperature was 250℃ and injection rate was 297mm/s. Thereby, high quality
substrate and cover plate could be manufactured efficiently. |
