| 棣栭〉 | 璧勮涓績(jī) | 鍖栧伐鍟嗚錘 | 縐戝鐮旂┒ | 浜т笟鍙戝睍 | 浜烘墠浜ゆ祦 | 浼?xì)灞曚俊鎭?/a> | 瀹炵敤緗戝潃 | 緹よ嫳鑱氶 | 瀛﹁呬粙緇?/a> | 浼?xì)鍛樹(shù)腑蹇?jī) | 璁哄潧 | ||
 | 濉戞枡 | 姍¤兌 | 綰ょ淮 | 娑傛枡涓庢補(bǔ)澧?/a> | 鑳剁矘鍓?/a> | 澶嶅悎鏉愭枡 | 鐭沖寲 | 鍖栧伐 | 浠櫒浠〃 | 鏂頒駭涓?/a> | 涓撻 | 榪斿洖棣栭〉 |
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| 棣栭〉 | 璧勮涓績(jī) | 鍖栧伐鍟嗚錘 | 縐戝鐮旂┒ | 浜т笟鍙戝睍 | 浜烘墠浜ゆ祦 | 浼?xì)灞曚俊鎭?/a> | 瀹炵敤緗戝潃 | 緹よ嫳鑱氶 | 瀛﹁呬粙緇?/a> | 浼?xì)鍛樹(shù)腑蹇?jī) | 璁哄潧 | ||
| 濉戞枡 | 姍¤兌 | 綰ょ淮 | 娑傛枡涓庢補(bǔ)澧?/a> | 鑳剁矘鍓?/a> | 澶嶅悎鏉愭枡 | 鐭沖寲 | 鍖栧伐 | 浠櫒浠〃 | 鏂頒駭涓?/a> | 涓撻 | 榪斿洖棣栭〉 |
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銆銆80騫翠唬鍒濓紝涓浗灝卞紑濮嬩簡(jiǎn)琛ㄩ潰澧炲己鎷夋浖(SERS)鐨勭浉鍏崇爺絀跺伐浣溿傝繎鍑犲勾瓚婃潵瓚婂鐨勮棰樼粍韙忓叆榪欎釜棰嗗煙錛屽嚑涔庡憟鎸囨暟澧為暱銆傛嵁鎮(zhèn)夛紝浠呭氨鈥滆〃闈㈠寮衡濅竴涓叧閿瘝鎼滅儲(chǔ)錛屾瘡騫村彂琛ㄧ殑鐩稿叧瀛︽湳璁烘枃宸茬粡杈懼埌2000澶氱瘒銆?
銆銆鍦⊿ERS鐨勭爺絀墮鍩燂紝鏈夊緢澶т竴閮ㄥ垎浜烘槸鍋氭潗鏂欏悎鎴愮殑錛屼粬浠殑璁烘枃閫氬父鍙槸璇佹槑鍚堟垚鐨勬潗鏂欐湁琛ㄩ潰澧炲己鎷夋浖鐨勬ц川錛岀劧鍚庡緢澶氬氨姝ゆ墦浣忥紝杞垬鏂扮殑鏉愭枡;浣嗘槸鏈変竴閮ㄥ垎浜哄嵈鎵х潃鑰曡樺湪SERS浣撶郴鐨勬柟娉曞拰鏈虹悊鐨勭爺絀訛紝鍘﹂棬澶у鐨勪換鏂屾暀鎺堝氨鏄繖鍏朵腑鐨勪竴浣嶃?
銆銆鎴戝浗SERS棰嗗煙鐨勭爺絀垛滄寔緇崌娓┾?/strong>
銆銆1928騫達(dá)紝鍗板害鐗╃悊瀛﹀鎷夋浖(Raman)棣栨鍦ㄥ疄楠屼腑瑙傚療鍒版媺鏇兼暎灝勫厜錛屽茍鍥犳鑽ｈ幏浜?930騫寸殑璇鴻礉灝?dāng)鐗╃悊瀛﹀銆傝櫧鐒跺湪1928騫村埌1945騫翠箣闂達(dá)紝鎷夋浖鍏夎氨鍦ㄧ墿璐ㄧ粨鏋勭殑鐮旂┒涓彂鎸ヤ簡(jiǎn)閲嶈鐨勪綔鐢紝浣嗕俊鍙峰急榪欎釜涓庣敓淇辨潵鐨勭己鐐瑰湪寰堝ぇ紼嬪害涓婇檺鍒朵簡(jiǎn)鍏跺湪鍚勬柟闈㈢殑搴旂敤銆傜洿鍒幫紝1974騫達(dá)紝Fleischmann 絳変漢絎竴嬈″湪鍚″暥鍚擱檮鐨勭矖緋欓摱鐢墊瀬涓婅瀵熷埌SERS淇″彿銆傜敱浜庤〃闈㈠寮烘晥搴斿彲浠ヤ嬌鎷夋浖寮哄害澧炲ぇ鍑犱釜鏁伴噺綰э紝鎻愪緵浜?jiǎn)鏋侀珮鐨勮〃闈個(gè)嫻嬬伒鏁忓害錛屼負(fù)浜轟滑鍒葷敾浜?jiǎn)寰堝ソ鐨勫簲鐢ㄥ墠鏅Q屽湪鍥介檯涓婂緢蹇氨鎺璧蜂簡(jiǎn)SERS鐮旂┒鐨勭儹娼?
銆銆鎹換鏂屾暀鎺堜粙緇嶏紝80騫翠唬鍒濓紝SERS鍙戝睍鐨勫垵鏈燂紝涓浗灝卞凡緇忔湁縐戝瀹跺紑濮婼ERS鐨勫伐浣溿傛瘮濡傦紝褰撴椂鐗╃悊鎵鐨勫紶楣忕繑鑰佸笀銆佽嫃宸炲ぇ瀛︾殑欏句粊鏁栬佸笀絳夛紝鍏朵腑欏句粊鏁栬佸笀榪樹(shù)笓紼嬪幓綰界害瀛︿範(fàn)SERS鐨勭浉鍏崇煡璇嗐?
銆銆1987騫達(dá)紝鐢頒腑緹よ佸笀鍥炲浗涔嬪悗錛屽湪鍘﹂棬澶у寮濮嬬數(shù)鍖栧浣撶郴鍜岃繃娓￠噾灞炰綋緋葷殑SERS鐮旂┒銆?
銆銆浠庣墿鐞嗘墍鍑烘潵鐨勮佸笀鍒嗘暎鍒板叏鍥藉悇鍦幫紝鎺ㄥ姩浜?jiǎn)鍏ㄥ浗涓嶅悓鍦板煙鐨凷ERS鐮旂┒;浠庣敯涓兢鑰佸笀璇鵑緇勶紝鍚夋灄澶у鐨勮檔鍐板拰寰愯敋闈掕佸笀璇鵑緇勬瘯涓氭垨榪涗慨鍚庣殑鐮旂┒浜哄憳錛屾帹鍔ㄤ簡(jiǎn)鍥藉唴鐨凷ERS鐮旂┒錛屽艦鎴愪簡(jiǎn)浠婂ぉ瑙勬ā錛屽茍鍦ㄥ浗闄呬笂鍗犳嵁浜?jiǎn)閲嶈鐨勪竴甯箣鍦般?
銆銆浠嶴ERS鐮旂┒浜哄憳鐨勯鍩熷垎甯冩潵鐪嬶紝鐗╃悊棰嗗煙鐨勭爺絀惰呭紑濮嬫棩鐩婂噺灝戯紝鑰屽寲瀛﹀拰鐢熺墿鍖誨鏂歸潰鐨凷ERS搴旂敤鐮旂┒鐨勪漢鍛樻瘮渚嬪垯鍦ㄤ笉鏂鍔犮傚帵闂ㄥぇ瀛︺佸悏鏋楀ぇ瀛︺佽嫃宸炲ぇ瀛︺佷腑縐戦櫌鐗╃悊鎵絳夋垚涓鴻棰嗗煙鍏鋒湁閲嶈褰卞搷鍔涚殑鍗曚綅銆?
銆銆浠繪枌鏁欐巿浠嬬粛鍒幫紝鈥滆繎騫達(dá)紝鍥介檯涓婁粠浜婼ERS鐮旂┒鐨勪漢鍛樺嚑涔庡憟鎸囨暟澧為暱銆備粖騫村彧鏄互鈥樿〃闈㈠寮衡欑殑鍏抽敭璇嶅幓鎼滅儲(chǔ)錛屼竴騫村凡緇忔湁2000澶氱瘒鏂囩珷錛岃繖宸茬粡鏄竴涓潪甯稿ぇ鐨勭爺絀墮鍩熶簡(jiǎn)銆傗?
銆銆鎹粙緇嶏紝鍥藉唴澶栭兘鏈変竴浜涢噸瑕佺殑瀛︽湳浼?xì)璁负SERS浜哄憳鎻愪緵浜?jiǎn)閲嶈鐨勪氦娴侐q沖彴銆傛瘮濡備袱騫翠竴嬈＄殑鍏ㄥ浗鍏夋暎灝勫鏈細(xì)璁拰鍥介檯鎷夋浖鍏夎氨澶т細(xì)錛孲ERS閮芥槸鍏朵腑鏈澶х殑鍒嗕細(xì)銆傚洓宸濆ぇ瀛﹀皢涓誨姙2015騫寸殑鍏ㄥ浗鍏夋暎灝勫鏈細(xì)璁紝浠婂勾鐨勫浗闄呮媺鏇煎ぇ浼?ICORS)宸茬粡鍦ㄥ痙鍥借舵嬁鍙紑錛岃妯″皢杈懼埌900澶氫漢銆備換鏂屾暀鎺堝皢涓撶▼鍓嶅線鍙傚姞銆?
銆銆SERS鐮旂┒鐨勨滅儹鐐光濅笉絳変簬鈥滃叧閿偣鈥?/strong>
銆銆榪戝勾鏉ワ紝SERS棰嗗煙鐨勭爺絀垛滃鐏鑽尖濄備換鏂屾暀鎺堣錛岀幇鍦⊿ERS棰嗗煙鏈閲嶈鐨勭爺絀舵柟鍚戞槸SERS鍩哄簳鐨勫埗澶囥備粠鏈鍒濈殑鐢?shù)鍖栧绮椌p?娌夋穩(wěn)銆佺湡絀烘矇娣(wěn)鏂規(guī)硶錛屽埌綰崇背綺掑瓙鐨勫悎鎴愩傞殢鐫綰崇背縐戝鐨勫彂灞曪紝浜轟滑鍙互綺懼閥鐨勬帶鍒剁撼綾崇粨鏋勭殑緇勬垚銆佸艦鐘躲佸ぇ灝忥紝騫惰兘鏈夊簭鐨勫鍏惰繘琛岀粍瑁呫傚緱鐩婁簬姝わ紝鍒╃敤SERS浜轟滑鑾峰緱浜?jiǎn)鍗曞垎瀛愮殑妫嫻嬬伒鏁忓害錛屽彇寰椾簡(jiǎn)紿佺牬鎬х殑榪涘睍銆傛渶榪戯紝澹沖眰闅旂粷綰崇背綺掑瓙澧炲己鎷夋浖鍏夎氨(SHINERS)鐨勭爺絀惰繘涓姝ユ嫇瀹戒簡(jiǎn)SERS鐨勫簲鐢ㄩ鍩熴傚悓鏍峰埄鐢ㄨ〃闈㈢瓑紱繪縺鍏冨寮哄師鐞嗙殑閽堝皷澧炲己鎷夋浖鍏夎氨(TERS)鎶鏈洜鍏墮珮絀洪棿鍒嗚鯨鐜囦篃寰楀埌浜?jiǎn)杩呯寷鐨勫彂灞曘傝繖浜涜繘灞曡繘涓姝ユ帹鍔ㄤ簡(jiǎn)SERS鎶鏈湪鍩虹鐮旂┒鍜屽伐涓氬簲鐢ㄩ鍩熺殑騫挎硾搴旂敤銆?
銆銆SERS鐨勫彟澶栦竴涓爺絀剁儹鐐規(guī)槸鍦ㄩ珮鐏墊晱鍒嗘瀽涓殑搴旂敤錛屾秹鍙?qiáng)鍏跺湪椋熷搧瀹夊叏銆佺幆澧冦佸叕鍏卞崼鐢熺瓑棰嗗煙鐨勫垎鏋愬簲鐢ㄧ爺絀躲?
銆銆涓嶈繃錛屸滅儹鐐逛笉絳変簬鍏抽敭鐐癸紝鈥濅換鏂屾暀鎺堣錛屸淪ERS鐮旂┒鐨勫叧閿湪浜庡浣曢氳繃瀵規(guī)満鐞嗗拰鏈哄埗鐨勭爺絀訛紝鍙戝睍鏂規(guī)硶錛屾彁楂樺叾閲嶇幇鎬с佸彲闈犳с傗濇嵁浠嬬粛錛屽湪鍏夋暎灝勪笓涓氬鍛樹(shù)細(xì)鐨勭粍緇囦笅錛屾瘡騫村湪鍥藉唴閮藉彫寮涓嬈″皬瑙勬ā鐨凷ERS鐮旇浼?xì)锛屼笓闂ㄨ璁篠ERS棰嗗煙瀛樺湪鐨勬寫(xiě)鎴樻у拰浜熷緟瑙ｅ喅鐨勫叧閿棶棰樸?
銆銆鈥滀粠鎴戜釜浜虹悊瑙ｏ紝鎴戣涓篠ERS鐢ㄤ簬瀹氶噺鍒嗘瀽榪樻湁寰堣繙鐨勮礬闇瑕佽蛋錛屽洜涓鴻繕娌℃湁浠涔堟妧鏈彲浠ヤ繚璇丼ERS瀹氶噺鍒嗘瀽鐨勫彲闈犳с傜幇鍦ㄧ‘瀹炴湁浜涙姤閬撹〃鏄庡湪涓涓緢灝忕殑嫻撳害鑼冨洿鍐呭彲浠ヨ幏寰椾笉閿欑殑綰挎х浉鍏崇郴鏁幫紝浣嗚瑙ｅ喅瀹氶噺闂錛屽繀欏諱弗鏍兼寜鐓у垎鏋愭柟娉曠殑鏍囧噯紼嬪簭鍘誨仛銆傝鎴愪負(fù)鏍囧噯鏂規(guī)硶闇瑕佽繘琛屽悇鏂歸潰鐨勯獙璇侊紝姣斿涓嶅悓鐨勬牱鍝併佷笉鍚屾壒嬈＄殑鍚岀被鏍峰搧銆佷笉鍚岀殑浣撶郴銆佹湁鏃犲共鎵扮殑鎯呭喌涓嬫槸鍚﹂兘鍙互寰楀埌鍙潬鐨勭粨鏋溿傚惁鍒欙紝鐮旂┒宸ヤ綔鍙兘鍋滅暀浜庢枃绔狅紝闅句互寰楀埌瀹為檯搴旂敤銆傗?
銆銆鈥滃畾閲忓垎鏋愶紝涓鐩存槸SERS棰嗗煙涓涓寫(xiě)鎴樸傝皝瑕佺湡姝ｈВ鍐充簡(jiǎn)瀹氶噺鐨勯棶棰橈紝浠栦篃灝卞彂璐簡(jiǎn)銆傗濅換鏂屾暀鎺堝紑鐜╃瑧鍦拌銆?
銆銆鎺ョ潃浠栧垎鏋愬埌錛屸滅撼綾蟲(chóng)潗鏂欎笉鍚屼綅鐐圭殑澧炲己鏁堝簲涓嶅悓錛岀矑瀛愰潬榪戯紝鑰﹀悎鍜屽寮烘晥搴斿氨寮猴紝鍙嶄箣灝卞急銆傚洜姝わ紝SERS鐨勫畾閲忓垎鏋愰瑕佺殑鎸?xiě)鎴樻槸瑙ｅ啗_寮哄熀搴曠殑鍧囦竴鎬у拰鍙潬鎬с傗?
銆銆鈥滃彟澶栬繕鏈変竴涓叧閿棶棰樻槸媯(gè)嫻嬫柟娉曠殑閫夋嫨鎬с傚鏋滄病鏈変紭寮傜殑閫夋嫨鎬э紝鏃犳硶搴旂敤浜庡疄闄呭鏉傜殑浣撶郴銆傛媺鏇煎緱鍒扮殑鏄垎瀛愯嚜韜殑鎸囩汗淇℃伅錛屾墍鏈夌殑鎺ヨ繎SERS鍩哄簳鐨勫垎瀛愰兘琚寮恒傛鍥犲姝わ紝鍦ㄥ鏉備綋緋諱腑涔熷皢鑾峰緱澶ч噺鐩鎬簰騫叉壈鐨勪俊鎭紝鐢氳嚦浜庡彈鍏朵粬鍒嗗瓙绔炰簤鍚擱檮鐨勫獎(jiǎng)鍝嶏紝鏃犳硶鑾峰緱寰呮祴鍒嗗瓙鐨勪俊鍙楓傚洜姝わ紝蹇呴』鍙戝睍鏂規(guī)硶錛屽彧璁╁緟嫻嬬墿璐ㄥ瘜闆嗗埌琛ㄩ潰榪涜岃媯(gè)嫻嬪埌銆傗?
銆銆闄ゆ涔嬪錛岃繕鏈変竴涓滄湁鏁堟湡鈥濈殑闂錛屼換鏂屾暀鎺堣錛屸滃鏋滃悎鎴愮殑澧炲己璇曞墏鏀劇疆涓孌墊椂闂村氨鈥樺彉璐ㄢ欎簡(jiǎn)錛屽啀楂樺啀鍧囦竴鐨勫寮鴻‖搴曢兘娌℃湁鎰忎箟銆傗?
銆銆鈥滃浜庡熀搴曞埗澶囧強(qiáng)鍏垛樻湁鏁堟湡鈥欙紝鐩墠榪樻病鏈変換浣曟爣鍑嗭紝鏍囧噯濮旇繖杈逛篃榪樺鍦ㄨ澶у鎻愬緩璁殑闃舵銆傗?
銆銆鏄劇劧SERS棰嗗煙榪樺瓨鍦ㄤ笉灝戦棶棰橈紝浣嗘槸涔熸鏄洜涓哄姝わ紝璇存槑榪欎釜瀛︾鍏呮弧媧誨姏錛岃繕鏈夊緢澶氫簨鎯呭彲浠ュ仛銆傗滃鏋滆В鍐充簡(jiǎn)浠ヤ笂鐨勯棶棰橈紝SERS灝嗘潵浼?xì)闈炲父鏈夌敤锛屽彲浠ヨ鍘熸潵鑽у厜鑳界敤鐨勯鍩熷Q孲ERS鍩烘湰閮藉彲浠ョ敤銆傗濅換鏂屾暀鎺堣銆?
銆銆SERS鍩哄簳鐨勪駭涓氬寲寰堥毦
銆銆鍥藉宸茬粡鏈夊晢鍝佸寲鐨凷ERS鍩哄簳鍜屽寮鴻瘯鍓傦紝鑰屽浗鍐呰繖鏂歸潰榪樻湁涓瀹氱殑璺濈銆傝櫧鐒跺緢澶氳棰樼粍閮藉湪鐮旂┒SERS鍦ㄤ笉鍚岄鍩熺殑搴旂敤錛屼絾鏄粷澶у浠呴檺浜庡疄楠屽鐮旂┒闃舵錛屾槸閽堝鏌愪竴涓牱鍝佸湪鏌愪竴涓壒瀹氭潯浠舵垨鑰呯幆澧冧笅鐨勪嬌鐢ㄣ?
銆銆鎹換鏂屾暀鎺堜粙緇嶏紝2011騫磋搗錛屼負(fù)浜?jiǎn)淇?jī)榪涚瓑紱繪縺鍏冨寮烘媺鏇煎厜璋?PERS)鐨勫簲鐢紝鐢頒腑緹ら櫌澹琛旂殑浠櫒鐮斿彂鍙?qiáng)搴旂敤椤圭洰鎵鐮斿彂鐨勫３灞傞殧紱葷撼綾崇矑瀛愬寮烘媺鏇煎厜璋?SHINERS)綺掑瓙宸茬粡鍦ㄩ攢鍞備粠鏂囩尞涓紝铏界劧鐪嬪埌鍥藉唴涓埆鍗曚綅澹扮О宸茬粡鑾峰緱寰堝ソ鐨勫寮鴻‖搴曪紝浣嗘槸鐩墠榪樻病鏈夌湅鍒板緢濂界殑瀹為檯搴旂敤瀹炰緥鍜屼駭鍝併?
銆銆瀵逛簬鍥藉唴SERS鍩哄簳鐨勪駭涓氬寲錛屼換鏂屾暀鎺堣鈥滄寫(xiě)鎴樹(shù)粛鍦ㄢ濓紝鎺ョ潃浠栧垎鏋愪簡(jiǎn)鍘熷洜錛?
銆銆鈥滅洰鍓嶅晢鍝佸寲鐨凷ERS鍩哄簳铏界劧鍧囦竴鎬ц緝濂斤紝浣嗗寮烘晥搴旀櫘閬嶈緝寮憋紝涓嶈兘鍙戞尌SERS鐙壒鐨勪紭鍔褲傚彟澶栵紝浣縎ERS鍩哄簳瀵圭洰鏍囨嫻嬬墿鍏鋒湁鏋侀珮鐨勯夋嫨鎬ф槸鑰冨療SERS鍩哄簳鐨勪竴涓噸瑕佺殑鎸囨爣銆傗濇嵁鎮(zhèn)夛紝鐩墠PERS欏圭洰緇勶紝宸茬粡鍦ㄥSHINERS綺掑瓙榪涜鍔熻兘鍖栫殑淇グ錛屽凡緇忚繘鍏ュ疄闄呮牱鍝佸垎鏋愰樁孌碉紝浣嗕篃榪樻湭鍒頒駭涓氬寲闃舵銆?
銆銆鈥淪ERS鍩哄簳浜т笟鍖栫殑闅懼害鍦ㄤ簬鍩哄簳涓嶅悓浣嶇偣闂村寮烘晥搴旂殑宸埆鍙互杈懼嚑涓暟閲忕駭錛岃繖灝辮姹係ERS鍩哄簳鐨勪駭涓氬寲鍒跺榪囩▼涓兘澶熷疄鐜板潎鍖鎬х殑楂樺害鍙帶銆傜洰鍓嶈繕娌℃湁涓涓畬緹庣殑鏂規(guī)硶鍙互鑾峰緱楂樺寮烘晥搴斿潎鍖鎬х殑琛簳錛岃繖浠嶆槸SERS棰嗗煙鐨勬寫(xiě)鎴樻х殑璇鵑錛岀洰鍓嶄粛鏈変笉灝戠殑浜哄湪鍔姏銆傗?
銆銆鎵嬫寔寮忔媺鏇煎厜璋變?nèi)A鐨勬湭鏉ュ懡榪愪笌SERS鍩哄簳鈥滀紤鎴氱浉鍏斥?/strong>
銆銆鎷夋浖鍏夎氨浠浘緇忔槸縐戠爺瀹為獙瀹や腑鐨勯珮绔華鍣紝鍏朵環(huán)鏍間篃鏇劇粡鈥滈珮?shù)笉鍙強(qiáng)鈥濄傜洰鍓嶏紝鍗曟嘗闀跨殑鍏辮仛鐒︽樉寰媺鏇煎厜璋變?nèi)A鍣ㄧ殑浠鋒牸宸茬粡闄嶅埌浜?jiǎn)鐧句竾鍏冧互鍐呭Q屼篃宸茬粡鍦ㄧ鐮旀満鏋勩佸垎鏋愭嫻嬩腑蹇?jī)鍜岄噸瑕佺殑浼佷笟寰楀堫C簡(jiǎn)騫挎硾鐨勫簲鐢紝浣嗘槸紱葷湡姝ｇ殑鏅強(qiáng)榪樻湁涓瀹氱殑璺濈銆傛墜鎸佸紡鎷夋浖鍏夎氨浠敱浜庡叾浣跨敤鏂逛究錛屼環(huán)鏍間究瀹滆屽彈鍒頒笉灝戝崟浣嶇殑闈掔潗錛岀壒鍒湪鍏畨銆佹搗鍏熾佽冨彜絳夊崟浣嶅緱鍒板疄闄呭簲鐢ㄣ傚湪HORIBA鎷夋浖瀛﹂櫌涓緢澶氳佸笀浠嬬粛浜?jiǎn)渚挎惡寮忔媺鏇间华鍣ㄧ殑搴旂敤浠ュ強(qiáng)鏈潵鐨勫彂灞曘?
銆銆鈥滄墜鎸佸紡鎷夋浖鏈潵甯?jìng)鍦哄法澶уQ屸濅換鏂屾暀鎺堜粙緇嶅埌錛屸滄墜鎸佸紡鎷夋浖浠櫒鐨勭伒鏁忓害榪滀綆浜庡ぇ鍨嬪叡鑱氱劍鎷夋浖浠櫒銆傚洜姝わ紝渚挎惡浠櫒搴旂敤閫氬父灞闄愪簬涓浜涚函鏍峰搧鐨勬嫻嬶紝瀵逛簬嫻撳害杈冧綆鐨勬牱鍝佺殑媯(gè)嫻嬭繕姣旇緝鍥伴毦銆傜洰鍓嶇殑搴旂敤棰嗗煙涔熸瘮杈冨眬闄愶紝濡傛瘨鍝佹嫻嬬瓑銆傝屽浜庡緢澶氭秹鍙?qiáng)鍥借姘戠敓鐨剫箵搴︽瘮杈冧綆鐨勫鏉傛牱鍝佺殑妫嫻嬶紝濡傛灉娌℃湁SERS澧炲己鏁堝簲鍑犱箮鏄笉鍙兘瀹屾垚銆傛垜鐩鎬俊錛岄殢鐫閽堝渚挎惡浠櫒鐨凷ERS搴旂敤鏂規(guī)硶鐨勫彂灞曪紝鎵嬫寔寮忔媺鏇煎厜璋變?nèi)A灝嗚繋鏉ュ叾鈥樻槬澶┾欍傗?
銆銆濡傛鐪嬫潵錛屾墜鎸佸紡鎷夋浖鍏夎氨浠湭鏉ョ殑搴旂敤鍓嶆櫙涓嶴ERS鐨勮繘灞曗滀紤鎴氱浉鍏斥濄備換鏂岃〃紺猴紝鎵嬫寔寮忎華鍣ㄧ殑鎶鏈棬妲涜緝浣庯紝鍥藉唴涓庡浗澶栫殑鐮斿彂姘村鉤宸埆宸茬粡寰堝皬浜?jiǎn)锛屾渶緇堝簲鐢ㄥ皢鍐沖畾浜庡寮烘簮錛屾病鏈夊寮烘簮榪欏彴浠櫒鍑犱箮灝扁滃簾鈥濅簡(jiǎn)銆?