It is possible that the hydrophobic guest within amphiphilic polymer
micelles may leak out and be captured by other species before polymer micelles adhere
to the desired focus because of the complexity in an actual release procedure, rendering
the reduced efficiency of the nanocarrier system. To describe such a scenario, two watersoluble
fluorescent amphiphilic random copolymers of PAV and PAA with photo-crosslinkable
coumarin and anthracene pendants, respectively, were chosen to investigate the
equilibrating immigration and maleimide-anthracene-based Diels?Alder-trapping of
hydrophobic octylmaleimide guest from one type of photo-cross-linked polymer micelles
of PAV85% to another of PAA66% in aqueous solution using the emission and absorption
spectra techniques.
