The amphiphilic random copolymer of P(NVPco-
NHPSS) with photocleavable N?O sulfonate side groups
has been prepared to investigate the light-triggered disruption
of copolymer micelles. Methods of absorption and emission
spectra, solution transmittance, dynamic light scattering
(DLS), and transmission electron microscopy (TEM) were
applied. It was found that P(NVP-co-NHPSS) could form
polymeric nanoaggregates in aqueous solution. And the
photocleavage of the N?O bond within copolymer micelles
upon 365 nm UV light could be conveniently controlled by
changing the irradiation intensity, leading to the disruption of
copolymer micelles and the photocontrolled release of Nile
red encapsulation. And by encapsulating NaLuF4:Gd/Yb/Tm
UCNPs inside copolymer micelles, the response of the photocleavable N?O bond to the 980 nm laser was much weaker than
the response to 365 nm light; however, the photocontrolled release of Nile red could still be effectively triggered by the NIR light
of the 980 nm laser.
