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Three organotin carboxylates based on amide carboxylic acids: (Ph3Sn)2(L1) (1) (L1
? 3,30-(1,3,5,7-
tetraoxo-5,7-dihydropyrrolo[3,4-f]isoindole-2,6(1H,3H)-diyl)dipropionic acid), (Ph3Sn)2(L2)$C7H8 (2)
(L2 ? 3,30-(1,3,6,8-tetraoxo-1,3,6,8-tetrahydrobenzo [lmn][3,8]phenanthroline-2,7-diyl)dipropionic acid),
[(Ph3Sn)(CH3CH2O)]2(L3) (3) (L3 ? 2,20-(1,3,5,7-tetraoxo-5,7-dihydropyrrolo[3,4-f]isoindole-2,6(1H,3H)-
diyl) dibenzoic acid) were synthesized and characterized by elemental analysis, IR, 1H, 13C, 119Sn NMR
spectroscopy and X-ray crystallography diffraction analyses. Complexes 1e3 are di-nuclear triphenlytin
carboxylates owning “S” shaped monomer structures. Ligands in 1e3 adopt unidentate coordination.
Intermolecular hydrogen bonds and Sn$$$O interactions help complexes 1e3 build their supramolecular
structures which are discussed in detail. The preliminary antitumor activities of 1e3 against HepG2 cell
lines have also been studied. |
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