Calcium-dependent and -independent annexin V binding: distinct molecular behaviours at cell membrane interfaces
writer：Yong-Hao Ma, Bolin Li, Jingjing Yang, Xiaofeng Han, Zhan Chen* and Xiaolin Lu*
keywords：annexin V binding, molecular behaviours, SFG, calcium
source：期刊
specific source：Chem. Commun., 2020, 56, 1653
Issue time：2020年
Distinct annexin V binding behaviours in Ca2+-dependent and Ca2+-independent cases were comparatively investigated using sum frequency generation vibrational spectroscopy. It was discovered that binding affected the molecular arrangement of both membrane leaflets, and the initial Ca2+-independent binding went through a transition with annexin V reorientation to a more stable state upon adding Ca2+.
https://pubs.rsc.org/en/content/articlelanding/2020/cc/c9cc09184j#!divAbstract