[Polym Chem] Glycopolymer-coated gold nanorods synthesised by a one pot copper(0) catalyzed tandem RAFT/click reaction
writer：Jiawei Lu, Weidong Zhang, Sarah-Jane Richards, Matthew I. Gibsonc, Gaojian Chen*
keywords：http://pubs.rsc.org/en/Content/ArticleLanding/2014/PY/c3py01526b#!divAbstract
source：期刊
specific source：Polym. Chem., 2014,5, 2326-2332
Issue time：2013年
Side-chain functionalized glycopolymers have been successfully prepared in a well-controlled manner via a copper(0)-catalyzed one-pot reaction combining living radical
polymerisation and ‘click chemistry’. The polymerisation was confirmed
by the first-order kinetic plots, the linear relationships between
molecular weights and the monomer conversions while keeping relatively
narrow polydispersity (<1.33). The click conversion and
polymerisation conversion versus reaction time plots for a
Cu(0)-catalyzed one-pot reaction elucidate that the rates of click
reaction are significantly faster than the polymerisation rates.
Modified gold nanorods (GNRs) with glycopolymeric coatings were prepared
through the interaction of Au–S bonds and the glycopolymer substituted
GNRs showed strong, specific molecular recognition abilities with lectin
(PNA).