[Soft Matter] Protease-promoted drug delivery using peptide-functionalized gold nanoparticles
作者：Wang, Jianhao; Yue, Yanan; Chen, Gaojian; et al.
關(guān)鍵字：CONTROLLED-RELEASE, CANCER-THERAPY, RESPONSIVE NANOCARRIERS, MESOPOROUS SILICA, CELLS
論文來源：期刊
具體來源：Soft Matter
發(fā)表時(shí)間：2011年
Gold nanoparticles functionalized with amphiphilic peptides can encapsulate Bodipy and release it by diffusion. Proteolytic cleavage of the peptide monolayer triggers the rapid release of the encapsulated Bodipy from nanoparticles to mammalian cells, representing a prototypical model of protease-promoted drug delivery using gold nanoparticles.