Highly Regioselective Isomerization-Hydroaminomethylation of Internal Olefins Catalyzed by Rh Complex with Tetrabi-Type Phosphorus Ligands.
writer：Guodu Liu, Kexuan Huang, Bonan Cao, Mingxin Chang, Shengkun Li, Le Zhou, Wenjun Wu,* Xumu Zhang.*
keywords：Isomerization-Hydroaminomethylation
source：期刊
specific source：Org. Lett. 2012, 14, 102–105. (DOI: 10.1021/ol202848a, communication, IF = 6.555, Citation: 28)
Issue time：2011年
A highly regioselective isomerization–hydroaminomethylation of internal olefins has been developed. A 95.3% amine selectivity and 36.2 n/i ratio were obtained for 2-octene with a Tetrabi ligand and Rh(acac)(CO)2, and a TON of linear amine was achieved of 6837 with a 39.1 n/i ratio of amine. The m-CF3-Ph substituted ligand was the best of the applied Tetrabi-type phosphorus ligands for different internal olefins, as up to a 99.2% amine selectivity and 95.6 n/i ratio were obtained for 2-pentene.