Highly Regioselective Hydroaminomethylation of Terminal Olefins to Linear Amines Using Rh Complexes with a Tetrabi Phosphorus Ligand.
作者：Guodu Liu, Kexuan Huang, Chaoxian Cai, Bonan Cao, Mingxin Chang, Wenjun Wu,* Xumu Zhang.*
關鍵字：regioselective Hydroaminomethylation
論文來源：期刊
具體來源：Chem-Eur. J. 2011, 17, 14559-14563. (DOI: 10.1002/chem.201103073, full paper, IF = 5.160, Citation:
發表時間：2011年
A highly regioselective hydroaminomethylation of terminal olefins catalyzed by Rh complexes with 2, 2′, 6, 6′‐tetrakis ((diphenylphosphino)methyl)‐1, 1′‐biphenyl (Tetrabi) ligand has been
developed. Up to 99?% amine selectivity, 168 linear/branched amine product ratio (n/i), and 97.4?% linear amine yield has been obtained at a substrate/rhodium precursor ratio (S/Rh) of 1000 with this methodology. The turnover number was achieved 6930 at 10000 S/Rh ratio,
and the n/i can reach up to >525. Several different olefins and secondary amines have been applied successfully with high chemoselectivity (99?%), yield (>98?%), and regioselectivity
(>120).