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【Journal of Materials Chemistry B】High-efficiency immunoassay platform with controllable surface roughness and oriented antibody immobilization
writer:Lingjie Song, Jie Zhao*, Shifang Luan*, Jiao Ma, Jinghua Yin, et al.,
keywords:oriented antibody immobilization, immunoassay
source:期刊
specific source:Journal of Materials Chemistry B, 2015, 3, 7499-7502
Issue time:2015年

Abstract:

High-efficiency immunoassay platforms with controlled surface roughness (single- and dual-scale structured surface) were prepared by combining a facile layer-by-layer particle deposition approach with oriented immobilization of antibodies through boronic acid moieties. The as-prepared surfaces showed significantly enhanced antibody loading capacity and antigen recognition, as proven by the fluorescent images.