Synthesis, self-assembly, and thermosensitive properties of ethyl cellulose-g-P(PEGMA) amphiphilic copolymers
作者：Yanxiang Li, Ruigang Liu*, Wenyong Liu, Hongliang Kang, Min Wu, Yong Huang*
關鍵字：Cellulose, graft copolymer, ATRP, thermal responsive
論文來源：期刊
具體來源：Journal of Polymer Science Part A: Polymer Chemistry 2008, 46, 6907-6915
發表時間：2008年
Ethyl cellulose graft poly(poly(ethylene glycol) methyl ether methacrylate) (EC-g-P(PEGMA)) amphiphilic copolymers were synthesized via atom transfer radical polymerization (ATRP) and characterized by FTIR, 1H NMR, and gel permeation chromatography. Reaction kinetics analysis indicated that the graft copolymerization is living and controllable. The self-assembly and thermosensitive property of the obtained EC-g-P(PEGMA) amphiphilic copolymers in water were investigated by dynamic light scattering, transmission electron microscopy, and transmittance. It was found that the EC-g-P(PEGMA) amphiphilic copolymers can self-assemble into spherical micelles in water. The size of the micelles increases with the increase of the side chain length. The spherical micelles show thermosensitive properties with a lower critical solution temperature around 65 °C, which almost independent on the graft density and the length of the side chains. The obtained EC-g-P(PEGMA) graft copolymers have both the unique properties of poly(ethylene glycol) and cellulose, which may have the potential applications in biomedicine and biotechnology.