課題組關于利用光控主客體相互作用改進具有“呼吸”特性的中空聚合物納米微球的制備并將其用于藥物控釋的研究工作被J. Mater. Chem. B錄用
Photo-controlled
host–guest interaction as a new strategy toimprove the preparation of
“breathing” hollow polymernanospheres as controlled drug delivery
Haitao
Zhang, Wei Tian,* RongtianSuo, Yang Yue, Xiaodong Fan, Zhen Yang, Hui Li,
Wanbin Zhang,and Yang Bai
This paper presents
the photo-controlled host–guest interaction between azobenzene and
β-cyclodextrin as a newstrategy to improve the method for core removal to
prepare poly((itaconoyloxy)ethylmethacrylate)-block-poly(Nisopropylacrylamide-based
hollownanospheres. This improved method for the preparation of hollow
nanospheres issimple,environment friendly, and highly efficient. The resulting
hollow nanospheres displayed a typical“breathing”behavior, which further
induces the controlled release of doxorubicin hydrochloride. Cellular toxicity
evaluation indicated that the hollow nanospheres possess good biocompatibility and
can be used as a promising doxorubicinhydrochloride carrier.
全文鏈接：http://pubs.rsc.org/en/content/articlelanding/2014/TB/C5TB01665G#!divAbstract