Preparation of Narrow or Monodisperse Poly(ethyleneglycol-g-acrylic acid) Microspheres with Ethylene Glycol Dimethacrylate As Crosslinker by Distillation-precipitation Polymerization
writer：hao Dai, Xinlin Yang*, Wenqiang Huang*
keywords：distillation precipitation polymerization; crosslinked functional microspheres; poly[(ethylene glycol)
source：期刊
specific source：Polym. Int., 56, 224-230 (2007). DOI: 10.1021/pi.2136
Issue time：2007年
Narrow-disperse or monodisperse poly{[poly(ethylene glycol) methyl ether acrylate]-co-(acrylic acid)} (poly(PEGMA-co-AA)) microspheres were prepared by distillation precipitation polymerization with ethyleneglycol dimethacrylate (EGDMA) as crosslinker with 2,2-azobisisobutyronitrile as initiator in neat acetonitrile in the absence of any stabilizer, without stirring. The diameters of the resultant poly(PEGMA-co-AA-co-EGDMA) microspheres were in the range 200–700nm with a polydispersity index of 1.01–1.14, which depended on the comonomer feed of the polymerization. The addition of the hydrogen bonding monomer acrylic acid played an essential role in the formation of narrow-disperse or monodisperse polymer microspheres during the polymerization.