Next-generation self-adhesive dressings: Highly stretchable, antibacterial, and UV-shielding properties enabled by tannic acidcoated cellulose nanocrystals
writer：Mingchen Yang, Chengling Huang, Hou-Yong Yu, Yanjuan Dong, Somia Yassin Hussain Abdalkarim
keywords：Rapid polymerization, Bilayer composites,Wound dressing
source：期刊
Issue time：2023年
Hydrogels with excellent high-water uptake and flexibility have great potential for wound
dressing. However, pure hydrogels without fiber skeleton faced poor water retention, weak
fatigue resistance, and mechanical strength to hinder the development of the dressing as nextgeneration functional dressings. We prepared an ultrafast gelation (6s) Fe3+/TA-CNC
hydrogel (CTFG hydrogel) based on a self-catalytic system and bilayer self-assembled
composites. The CTFG hydrogel has excellent flexibility (800% of strain), fatigue resistance
(support 60% compression cycles), antibacterial, and self-adhesive properties (no residue or
allergy after peeling off the skin). CTFG@S bilayer composites were formed after
electrospun silk fibroin (SF) membranes were prepared and adhesive with CTFG hydrogels.
The CTFG@S bilayer composites had significant UV-shielding (99.95%), tensile strain
(210.9 KPa), and sensitive humidity-sensing properties. Moreover, the integrated structure
improved the mechanical properties of electrospun SF membranes. This study would provide
a promising strategy for rapidly preparing multifunctional hydrogels for wound dressing.