PNIPAM Microgels for Biomedical Applications: From Dispersed Particles To 3D Assemblies
作者：Ying Guan and Yongjun Zhang*
關鍵字：microgel
論文來源：期刊
具體來源：Soft Matter, 2011, 7, 6375-6384. (invited review)
發表時間：2011年
Poly(N-isopropylacrylamide) (PNIPAM) microgel is perhaps the most well-known intelligent soft nanomaterial. Combining the strengths of hydrogel and nanoparticles, with unique stimuli-responsivity, PNIPAM microgels have found numerous biomedical applications, such as drug delivery, biosensing, and so on. Usually they were used as dispersed particles, however, they can also be used as building blocks to fabricate 2D films and 3D aggregates. These nanostructured assemblies exhibit new properties which the dispersed particles do not have, and new biomedical applications have been found for these assemblies. In this paper, the biomedical applications of PNIPAM microgels in the form of dispersed particles, 2D films and 3D aggregates were reviewed and some recent progress in this area was highlighted.