Direct Synthesis of Amphiphilic Block Copolymers from Glycidyl Methacrylate and Poly(ethylene glycol) by Cationic Ring-Opening Polymerization and Supramolecular Self-Assembly Thereof
writer：Huang, W.; Zhou, Y. F.; Yan, D. Y.*
keywords：block copolymers;cationic ring-opening polymerization;crosslinking;glycidyl methacrylate (GMA);polymeric core–shell micelles;self-assembly
source：期刊
specific source：J. Polym. Sci., Part A: Polym. Chem. 2005, 43, 2038. http://onlinelibrary.wiley.com/doi/10.1002/pola
Issue time：2005年
Amphiphilic block copolymers composed of hydrophilic poly(ethylene glycol) (PEG) block and hydrophobic poly(glycidyl methacrylate) (PGMA) block were synthesized through cationic ring-opening polymerization. By the control of the reaction time in the synthesis of block copolymer PEG-b-PGMA, a linear GMA block was obtained through the ring-opening polymerization of epoxy groups, whereas the double bond in GMA remained unreacted. The results show that the molecular weights of the PEG precursors have little influence on the grafting of GMA and the PGMA blocks almost keep the same length, despite the difference of PEG blocks. In addition, the PGMA blocks only consisted of several GMA units. The obtained amphiphilic block copolymers of PEG-b-PGMA could form core–shell polymeric micelles by direct molecular self-assembly in water, and the crosslinking of PGMA core of the micelles was also investigated.