Self-Assembly of Hyperbranched Polymers and Its Biomedical Applications
作者：Zhou, Y. F.; Huang, W.; Liu, J. Y.; Zhu, X. Y.; Yan, D. Y.
關鍵字：Hyperbranched Polymers,Biomedical Applications
論文來源：期刊
具體來源：Adv. Mater. 2010, 22, 4567. http://onlinelibrary.wiley.com/doi/10.1002/adma.201000369/pdf
發表時間：2010年
Hyperbranched polymers (HBPs) are highly branched macromolecules with a
three-dimensional dendritic architecture. Due to their unique
topological structure and interesting physical/chemical properties, HBPs
have attracted wide attention from both academia and industry. In this
paper, the recent developments in HBP self-assembly and their biomedical
applications have been comprehensively reviewed. Many delicate
supramolecular structures from zero-dimension (0D) to three-dimension
(3D), such as micelles, fibers, tubes, vesicles, membranes, large
compound vesicles and physical gels, have been prepared through the
solution or interfacial self-assembly of amphiphilic HBPs. In addition,
these supramolecular structures have shown promising applications in the
biomedical areas including drug delivery, protein
purification/detection/delivery, gene transfection,
antibacterial/antifouling materials and cytomimetic chemistry. Such
developments promote the interdiscipline researches among
surpramolecular chemistry, biomedical chemistry, nano-technology and
functional materials.