In this study, we developed a novel blending strategy, namely, the gradual blending method, to tune the micellar structure. Different from the most commonly used premixing blending method, which different block copolymers are premixed in a common solvent before their individual self-assembly, the gradual blending method involves gradually adding one type of block copolymer into the pre-generated micellar solution formed from another type of block copolymer. Moreover, we obtained a novel mesh-like vesicle from the self-assembly of the mixtures of P4VP43-b-PS260-b-P4VP43 and P4VP43-b-PS366-b-P4VP43 in 1,4-dioxane/water solution using the gradual blending method.